2019/7-至今    3044am永利集团官网vip   3044am永利集团官网vip   师资博士后   合作导师：刘中秋

2014/09-2019/06 中国药科大学 天然药物活性组分与药效国家重点实验室 硕博连读 导师：陈君

2010/09-2014/06 中国药科大学 中药学 学士

中药抗组织纤维化

• 1. 山茱萸环烯醚萜苷类成分通过上调溶酶体酸性脂肪酶抑制肝星状细胞活化的药效及作用机制，2021-01至2023-06，18万元，在研，主持

• 2. 山茱萸环烯醚萜苷类成分调控溶酶体酸性脂肪酶抗肝纤维化损伤的药效及作用机制, 2021-01至2022-12, 8万元, 在研, 主持

• 3. 丹参素调节谷氨酰胺分解代谢抑制肝星状细胞活化的研究, 2020-01至2022-12, 10万元, 在研, 主持

• 1. An, Lin; Lin, Yue-Fang; Li, Le-Yan; Kong, Mu-Yan; Lou, Yan-Mei; Wu, Jin-Jun*; Liu, Zhong-Qiu*. Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis. Front Pharmacol. 2021 Jan 22, 11:618262.

• 2. An, Lin; Peng, Li-Ying; Sun, Ning-Yuan; Yang, Yi-Lin; Zhang, Xiao-Wei; Li, Bin; Liu, Bao-Lin; Li, Ping; Chen, Jun. Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis. Antioxid Redox Signal, 2019, 30(15): 1831-1848.

• 3. An, Lin; Zhou, Mei; Marikar, Faiz M M T; Hu, Xue-Wen; Miao, Qiu-Yun; Li, Ping; Chen, Jun*. Salvia miltiorrhiza Lipophilic Fraction Attenuates Oxidative Stress in Diabetic Nephropathy through Activation of Nuclear Factor Erythroid 2-Related Factor 2. Am Journal Chin Med, 2017, 45(7): 1441-1457.

• 4. Peng, Li-Ying1; An, Lin1; Sun, Ning-Yuan; Ma, Yi; Zhang, Xiao-Wei; Liu, Wen-Hua; Liu, Bao-Lin; Li, Ping; Chen, Jun*. Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance. Am Journal Chin Med, 2019, 47(5): 1113-1131.

• 5. Zhang, Xiao-Wei; Zhang, Ping; An, Lin; Sun, Ning-Yuan; Peng, Li-Ying; Tang, Wei-Wei, Ma, Ding-Yuan*; Chen, Jun*. Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis. Acta Pharm Sin B. 2020, 10(8): 1397-1413.

• 6. Yang, Yu-Yu; Li, Xue-Yan; Peng, Li-Ying; An, Lin; Sun, Ning-Yuan; Hu, Xue-Wen; Zhou, Ping; Xu, Yong; Li, Ping*; Chen, Jun*. Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway. Biochim Biophys Acta Mol Basis Dis, 2018, 1864(3): 882-890.

• 7. Zhang, Xiao-Wei; Zhou, Mei; An, Lin; Zhang, Ping; Li, Ping; Chen, Jun*. Lipophilic Extract and Tanshinone IIA Derived from Salvia miltiorrhiza Attenuate Uric Acid Nephropathy through Suppressing Oxidative Stress-Activated MAPK Pathways. Am J Chin Med, 2020, 48(6): 1455-1473.

• 8. Tang, Wei-Wei; Huang, Bi-Xia; Wang, Jian-Cheng; An, Lin; Zhong, Huai-Ling; Yang, Hua; Li, Ping; Chen, Jun*. A label-free screening approach targeted protease-activated receptor 1 based on dynamic mass redistribution in living cells. RSC Advances, 2017, 7(68): 43005-43013.

• 9. Zhang, Xiao-Wei; Yang, Lin; An, Lin; Li, Ping; Chen, Jun*. Discovery of cancer cell proliferation inhibitors from Salviae miltiorrhizae radix et rhizoma by a trace peak enrichment approach. J Sep Sci, 2019, 42(2): 534-546.